ITT5950
ITT5950
- Catalog: ITT5950
- Gene/Protein: GYPC GLPC GPC
- Product Description: Immunotag™ CD236 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD236 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 11-60 |
| Specificity | The antibody detects endogenous CD236 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GYPC GLPC GPC |
| Accession No. | P04921 Q78HU7 |
| Alternate Names | Glycophorin-C (Glycoconnectin) (Glycophorin-D) (GPD) (Glycoprotein beta) (PAS-2') (Sialoglycoprotein D) (CD antigen CD236) |
| Description | glycophorin C (Gerbich blood group)(GYPC) Homo sapiens Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012], |
| Protein Expression | Blood,Liver,Spleen, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,membrane,cortical cytoskeleton, |
| Protein Function | function:This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin C plays an important role in regulating the stability of red cells.,online information:Blood group antigen gene mutation database,online information:Glycophorin C entry,polymorphism:GYPC is responsible for the Gerbich blood group system.,subcellular location:Linked to the membrane via Band 4.1.,tissue specificity:Glycophorin C is expressed in erythrocytes. Glycophorin D is ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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