ITT5974
ITT5974
- Catalog: ITT5974
- Gene/Protein: HDGF HMG1L2
- Product Description: Immunotag™ HDGF Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | HDGF |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 141-190 |
| Specificity | The antibody detects endogenous HDGF |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | HDGF HMG1L2 |
| Accession No. | P51858 P51859 |
| Alternate Names | Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2) |
| Description | hepatoma-derived growth factor(HDGF) Homo sapiens This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016], |
| Protein Expression | Brain,Epithelium,Hepatoma,Liver,Pituitary,Platelet, |
| Subcellular Localization | extracellular space,nucleoplasm,cytoplasm,transcriptional repressor complex, |
| Protein Function | domain:The PWWP domain harbors the heparin-binding sites and is responsible for DNA-binding, while the C-terminal region is essentially unstructured.,function:Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.,PTM:Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.,similarity:Belongs to the HDGF family.,similarity:Contains 1 PWWP domain.,subunit:Monomer, and domain-swapped homodimer.,tissue specificity:Ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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