ITT5977
ITT5977
- Catalog: ITT5977
- Gene/Protein: BMP1 PCOLC
- Product Description: Immunotag™ BMP-1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | BMP-1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 131-180 |
| Specificity | The antibody detects endogenous BMP-1 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | BMP1 PCOLC |
| Accession No. | P13497 P98063 |
| Alternate Names | Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP) |
| Description | bone morphogenetic protein 1(BMP1) Homo sapiens This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008], |
| Protein Expression | Brain,Placenta,Skin,Spleen, |
| Subcellular Localization | extracellular region,proteinaceous extracellular matrix,extracellular space,Golgi apparatus,membrane-bounded vesicle, |
| Protein Function | catalytic activity:Cleavage of the C-terminal propeptide at Ala-|-Asp in type I and II procollagens and at Arg-|-Asp in type III.,cofactor:Binds 1 zinc ion per subunit.,enzyme regulation:Activity is increased by the procollagen C-endopeptidase enhancer protein.,function:Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD).,similarity:Belongs to the peptidase M12A family.,similarity:Contains 2 EGF-like domains.,similarity:Contains 5 CUB domains.,tissue specificity:Ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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