ITT5981
ITT5981
- Catalog: ITT5981
- Gene/Protein: GSTA1
- Product Description: Immunotag™ GSTA1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GSTA1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human GSTA1. AA range:91-140 |
| Specificity | The antibody detects endogenous GSTA1 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GSTA1 |
| Accession No. | P08263 P13745 |
| Alternate Names | Glutathione S-transferase A1 (EC 2.5.1.18) (GST HA subunit 1) (GST class-alpha member 1) (GST-epsilon) (GSTA1-1) (GTH1) |
| Description | glutathione S-transferase alpha 1(GSTA1) Homo sapiens This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016], |
| Cell Pathway/ Category | Glutathione metabolism,Metabolism of xenobiotics by cytochrome P450,Drug metabolism, |
| Protein Expression | Brain,Liver, |
| Subcellular Localization | cytosol,extracellular exosome, |
| Protein Function | catalytic activity:RX + glutathione = HX + R-S-glutathione.,domain:The C-terminal domain may form a component of the hydrophobic substrate-binding site, but in contrast appears not to be directly involved in GSH binding and is not absolutely essential for catalytic activity.,function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.,similarity:Belongs to the GST superfamily.,similarity:Belongs to the GST superfamily. Alpha family.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,subunit:Homodimer or heterodimer of GSTA1 and GSTA2.,tissue specificity:Liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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