ITT5989
ITT5989
- Catalog: ITT5989
- Gene/Protein: NAPSA NAP1 NAPA
- Product Description: Immunotag™ Napsin A Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Napsin A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 191-240 |
| Specificity | The antibody detects endogenous Napsin A |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | NAPSA NAP1 NAPA |
| Accession No. | O96009 O09043 |
| Alternate Names | Napsin-A (EC 3.4.23.-) (Aspartyl protease 4) (ASP4) (Asp 4) (Napsin-1) (TA01/TA02) |
| Description | napsin A aspartic peptidase(NAPSA) Homo sapiens This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016], |
| Cell Pathway/ Category | Lysosome, |
| Protein Expression | Fetal lung,Kidney,Liver,Lung, |
| Subcellular Localization | extracellular space,lysosome,extracellular exosome,alveolar lamellar body,multivesicular body lumen, |
| Protein Function | function:May be involved in processing of pneumocyte surfactant precursors.,similarity:Belongs to the peptidase A1 family.,tissue specificity:Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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