ITT6002
ITT6002
- Catalog: ITT6002
- Gene/Protein: ADI1 MTCBP1 HMFT1638
- Product Description: Immunotag™ ADI1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ADI1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 71-120 |
| Specificity | The antibody detects endogenous ADI1 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ADI1 MTCBP1 HMFT1638 |
| Accession No. | Q9BV57 Q99JT9 Q562C9 |
| Alternate Names | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD) (Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1) (MTCBP-1) (Submergence-induced protein-like factor) (Sip-L) |
| Description | acireductone dioxygenase 1(ADI1) Homo sapiens This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015], |
| Cell Pathway/ Category | Cysteine and methionine metabolism, |
| Protein Expression | Adipose tissue,Fibroblast,Hepatoblastoma,Liver,Ovarian carcinoma,Placenta,T |
| Subcellular Localization | nucleus,cytoplasm,cytosol,plasma membrane, |
| Protein Function | cofactor:Binds 1 nickel ion per monomer. Can also use other divalent metal cations.,function:Has aci-reductone dioxygenase (ARD) activity and can function in the 5-methylthioadenosine (MTA) methionine salvage pathway. Down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.,pathway:Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from (S)-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.,similarity:Belongs to the acireductone dioxygenase (ARD) family.,subunit:Interacts with MMP14.,tissue specificity:Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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