ITT6014
ITT6014
- Catalog: ITT6014
- Gene/Protein: CD80 CD28LG CD28LG1 LAB7
- Product Description: Immunotag™ CD80 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD80 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 100-160 |
| Specificity | The antibody detects endogenous CD80 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CD80 CD28LG CD28LG1 LAB7 |
| Accession No. | P33681 Q00609 |
| Alternate Names | T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80) |
| Description | CD80 molecule(CD80) Homo sapiens The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011], |
| Cell Pathway/ Category | Cell adhesion molecules (CAMs),Toll_Like,Intestinal immune network for IgA production,Type I diabetes mellitus,Autoimmune thyroid disease,Systemic lupus erythematosus,Allograft rejection,Graft-versus-host disease,Viral myocarditis, |
| Protein Expression | Brain,Lymphoid,Synovial membrane tissue, |
| Subcellular Localization | intracellular,plasma membrane,external side of plasma membrane,cell surface,integral component of membrane,protein complex involved in cell adhesion, |
| Protein Function | function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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