ITT6030
ITT6030
- Catalog: ITT6030
- Gene/Protein: CEACAM1/CEACAM6/CEACAM8
- Product Description: Immunotag™ CD66a/b/c Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD66a/b/c |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 130-190 |
| Specificity | The antibody detects endogenous CD66a/b/c |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CEACAM1/CEACAM6/CEACAM8 |
| Accession No. | P13688/P40199/P31997 |
| Description | carcinoembryonic antigen related cell adhesion molecule 1(CEACAM1) Homo sapiens This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue thre |
| Protein Expression | Leukocyte,Liver,Plasma,Skin, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,cell-cell junction,adherens junction,basal plasma membrane,cell surface,membrane,integral component of membrane,apical plasma membrane,lateral plasma membra |
| Protein Function | disease:Increased serum levels of BGP-1 are found in individuals suffering from hepatic disorders.,disease:Loss or reduced expression is a major event in colorectal carcinogenesis.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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