ITT6041
ITT6041
- Catalog: ITT6041
- Gene/Protein: ICAM4 LW
- Product Description: Immunotag™ CD242 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD242 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 141-190 |
| Specificity | The antibody detects endogenous CD242 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ICAM4 LW |
| Accession No. | Q14773 Q9ERM2 |
| Alternate Names | Intercellular adhesion molecule 4 (ICAM-4) (Landsteiner-Wiener blood group glycoprotein) (LW blood group protein) (CD antigen CD242) |
| Description | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)(ICAM4) Homo sapiens This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008], |
| Protein Expression | Lung,Placenta, |
| Subcellular Localization | extracellular region,extracellular space,cytoplasm,plasma membrane,integral component of plasma membrane,integral component of membrane, |
| Protein Function | function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins.,online information:Blood group antigen gene mutation database,polymorphism:Responsible for the Landsteiner-Wiener blood group system. The molecular basis of the LW(A)=LW5/LW(B)=LW7 blood group antigens is a single variation in position 100; Gln-100 corresponds to LW(A) and Arg-100 to LW(B).,PTM:N- and O-glycosylated.,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Erythrocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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