ITT6045
ITT6045
- Catalog: ITT6045
- Gene/Protein: EREG
- Product Description: Immunotag™ Epiregulin Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Epiregulin |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 71-120 |
| Specificity | The antibody detects endogenous Epiregulin |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | EREG |
| Accession No. | O14944 Q61521 |
| Alternate Names | Proepiregulin [Cleaved into: Epiregulin (EPR)] |
| Description | epiregulin(EREG) Homo sapiens This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues. [provided by RefSeq, Jul 2015], |
| Cell Pathway/ Category | ErbB_HER, |
| Protein Expression | Colon adenocarcinoma,Pooled, |
| Subcellular Localization | extracellular region,extracellular space,intracellular,integral component of plasma membrane, |
| Protein Function | function:May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.,similarity:Contains 1 EGF-like domain.,tissue specificity:In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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