ITT6068
ITT6068
- Catalog: ITT6068
- Gene/Protein: FIG4 KIAA0274 SAC3
- Product Description: Immunotag™ FIG4 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FIG4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human FIG4. at AA range: 341-390 |
| Specificity | This antibody detects endogenous levels of FIG4 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | FIG4 KIAA0274 SAC3 |
| Accession No. | Q92562 Q91WF7 |
| Alternate Names | Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3) |
| Description | FIG4 phosphoinositide 5-phosphatase(FIG4) Homo sapiens The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008], |
| Subcellular Localization | Golgi membrane,endoplasmic reticulum,endosome membrane,integral component of membrane,early endosome membrane,late endosome membrane,recycling endosome, |
| Protein Function | phospholipid metabolic process, glycerophospholipid metabolic process, vacuole organization, behavior, locomotory behavior, cell death, death, organophosphate metabolic process, neuron differentiation, phosphoinositide metabolic process, pigmentation, glycerolipid metabolic process, neuron development, |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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