ITT6104
ITT6104
- Catalog: ITT6104
- Gene/Protein: ACO2
- Product Description: Immunotag™ ACO2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ACO2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human ACO2. at AA range: 421-470 |
| Specificity | ACO2 Polyclonal Antibody detects endogenous levels of ACO2 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ACO2 |
| Accession No. | Q99798 Q99KI0 |
| Alternate Names | Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) |
| Description | aconitase 2(ACO2) Homo sapiens The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Citrate cycle (TCA cycle),Glyoxylate and dicarboxylate metabolism, |
| Protein Expression | Brain,Cajal-Retzius cell,Fetal brain cortex,Skeletal muscle,Uterus, |
| Subcellular Localization | nucleus,mitochondrion,mitochondrial matrix,myelin sheath, |
| Protein Function | catalytic activity:Citrate = isocitrate.,cofactor:Binds 1 4Fe-4S cluster per subunit. Binding of a 3Fe-4S cluster leads to an inactive enzyme.,online information:Aconitase entry,pathway:Carbohydrate metabolism; tricarboxylic acid cycle.,similarity:Belongs to the aconitase/IPM isomerase family.,subunit:Monomer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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