ITT6143
ITT6143
- Catalog: ITT6143
- Gene/Protein: CDH17
- Product Description: Immunotag™ CDH17 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CDH17 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human CDH17 Polyclonal |
Specificity | This antibody detects endogenous levels of CDH17. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CDH17 |
Accession No. | Q12864 Q9R100 P55281 |
Alternate Names | Cadherin-17 (Intestinal peptide-associated transporter HPT-1) (Liver-intestine cadherin) (LI-cadherin) |
Description | cadherin 17(CDH17) Homo sapiens This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009], |
Protein Expression | Colon adenocarcinoma,Epithelium,Trachea, |
Subcellular Localization | plasma membrane,cell surface,membrane,integral component of membrane,basolateral plasma membrane, |
Protein Function | function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.,similarity:Contains 7 cadherin domains.,tissue specificity:Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |