Molecular Grinding Resin™ (35 Citations)
A Grinding Resin For Proteomics & Molecular Biology Applications
Molecular Grinding Resin™ has been specifically developed for effectively grinding small biological samples for the preparation and extraction of DNA, RNA and proteins. The resin consists of high tensile micro-particles, which effectively disrupt nuclei and other cell organelles.
Molecular Grinding Resin™ does not bind proteins or nucleic acids, minimizing loss. Unlike sand or other grinding materials, Molecular Grinding Resin™ is easy to work with and does not damage genomic DNA or high molecular mass proteins. Simply mix the biological sample with Molecular Grinding Resin™ and grind or homogenize the sample.
Molecular Grinding Resin™ is routinely used for isolation of 100kb genomic DNA and RNA. It can be used with any homogenization technique, including high speed mechanical grinders, such as Polytron, and high-energy sonicators.
For added convenience, Molecular Grinding Resin™ is also available with RNase-free disposable matching pestles and 1.5mL microfuge tubes (Cat. No. 786-138PR).
Supplied with enough resin for 200 isolations from 100mg tissue.
Features
- High tensile micro-particles for simple grinding & no damage to samples
- Minimizes loss: no binding of proteins or nucleic acids
- Disposable RNase-free matching pestles & 1.5mL microfuge tubes (Cat. No. 786-138PR)
Applications
- Grinding resin & tools for small samples, such as cells & tissues, for proteomics & molecular biology applications
- Preparation & extraction of DNA, RNA & proteins (isolation of 100kb genomic DNA & RNA)
- Use with any homogenization technique, including high-speed mechanical grinders & high-energy sonicators
Protocol | |
786-138 | |
786-138P | |
786-138PR |
Material Safety Data Sheet | |
786-138 | |
786-138P | |
786-138PR |
Technical Literature | |
Molecular Biology Handbook | A guide to our products for DNA and RNA. |
Protease & Phosphatase Inhibitors & Proteases Handbook | A handbook & selection guide for inhibitors of protease & phosphatases & for proteases & assays |
Sample Preparation Handbook | For Lysis Buffers, Fractionation, Dialysis, Protein Concentration and Enrichment |
- Chui, YC. et al (2023) Absence of Zika virus among pregnant women in Vietnam in 2008. TROP DIS TRAVEL MED VACCINES. https://doi.org/10.1186/s40794-023-00189-7
- Lajnaf, R. et al (2017) The effect of pH and heat treatments on the foaming properties of purified α-lactalbumin from camel milk. Colloids and Surfaces B. https://doi.org/10.1016/j.colsurfb.2017.05.002
- Lajnaf, R. et al (2017) The foaming properties of camel and bovine whey: the impact of pH and heat treatment. Food chemistry. https://doi.org/10.1016/j.foodchem.2017.07.064
- Barter, M.J. et al (2015) Stem Cell Epigenet. DOI: 10.1002/stem.2093
- Addington, C.P. et al (2014) Extracellular Matrix. 93:163
- Clarke, L.E. et al (2014) Arth. Res. Ther. 16:R67
- Rodriguez, A. et al (2014) J. Neuro. Sci. DOI: 10.1002/jnr.23353
- Chowdhury, A. et al (2013) BMC Musculoskel. Dis. 14:216
- Innes, J.F. et al (2013) Vetinary. J. 197:619
- Matthies, N. et al (2013) J. Tiss. Eng. Regen. Med. 7:965
- Adesida, A.B. et al (2012) PLOS. DOI: 10.1371/journal.pone.0039339
- Müller, J et al (2011) Rheumatology S3:003. doi:10.4172/2161-1149.S3-003
- Saliken, D.J.J. et al (2012) Arth. Res. 14:R153
- Müller, J et al (2011) Cell Transplant. 20:1589
- Myers, J.N. et al (2011) Cell Physiol. Biochem. 28:209
- Khan, W.S. et al (2010) J. Orthopaed. Res. 28:834
- Sung, H. et al (2010) Soft Matter. 6:5196
- Katopodi, T. et al (2009) Biomaterials 30:535
- Lochmatter, C. et al (2009) Parasitology. 136:487
- Garvican, E.R. et al (2008) J. Orthopaedic Res. 26:1133
- Khan, W.S. et al (2008) Arth. Res. Ther. 10:R74
- Kulick, A. et al (2008) Am J Physiol Renal Physiol 295:F37
- Oldershaw et al (2008) Stem Cells 26:666
- Qi, X. et al (2008) J. Clin. Invest. 118:173
- Adesida, A.B. et al (2007) Arth. Res. Ther. 9:R69
- Khan, W.S. et al (2007) Arthritis Res. Therap. 9:R55
- Marsano, A. et al (2007) Osteoarth. Cartil. 15:48
- Murdoch, A. et al (2007) Stem Cells 25:2786
- Varas, L. et al (2007) Stem Cells Develop. 16:965
- Whitaker, V. et al (2007) J Amer Soc Hort Sci 132:534
- Adesida, A.B. et al (2006) Arth. Res. Ther. 8:R61
- Doles, J. et al (2006) Develop. Biol. 295:13
- Tew, S.R. et al (2005) Osteoarth. Cart. 13:80
- Murriel, C. et al (2004) J Biol Chem 279:47985
- Schulze-Tanzil, G. et al (2004) Histochem. Cell Biol. 122:219