G-Biosciences' Immobilized p-Aminophenyl Phosphoryl Choline consists of a phosphoryl choline covalently linked to beaded agarose and is designed for the purification of C-reactive protein from plasma, ascites and other biological fluids.
CRP, C-reactive protein, is a pentameric protein found in the blood, the levels of which rise in response to inflammation, making CRP an acute-phase protein. Its physiological role is to bind to phosphocholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system.
More economical Immobilized O-Phosphorylethanolamine, an alternative to Immobilized p-Aminophenyl Phosphoryl Choline is also available. Immobilized O-Phosphorylethanolamine successfulyy purifies C-Reactive Protein.
Download the application note “Purification of C-Reactive proteins on G-Biosciences Immobilized O-Phosphorylethanolamine Resin” for more information.
- Ligand: p-aminophenyl phosphoryl choline
- Support: 6% crosslinked agarose
- Binding Capacity: >3mg human CRP/ml resin