Inhibitors/Activators
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Target
-- Any ---
SOD (superoxide dismutase)
STING
Glutaminase
Substrate / Probe
Adenylyl cyclase
Monoamine transporter
FABP (Fatty acid binding protein)
Tryptophan
GAP (GTPase activating protein)
Aquaporin
UBC (ubiquitin conjugating enzyme)
Glucose transporter
Protein demethylase
Methyltransferase
Bromodomain
Protein methyltransferase
Neddylation
Acyltransferase
UAE (ubiquitin activating enzyme)
Serine hydrolase
Dehydrogenase (ALDH, GDH, IDH, UGDH, DPD, DHPDH, and MDH)
RNA
DNA methylation
Inflammasome
DHFR (Dihydrofolate reductase)
Telomerase
DNA methyltransferase
Dehydrogenase (GAPDH, GPDH, IMPDH, PHGDH, LDH, DHODH)
Norepinephrine
Chaperone
(LOX) Lipoxygenase
Prions
PD-1
Reverse transcriptase inhibitor
PFKFB3 (6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3)
Molecular glue
Carboxypeptidase
NOS (Nitric oxide synthase)
TLR (Toll-like receptor)
Thromboxane
Galactosidase
Prolyl hydroxylase
Serotonin
Spin trap
Glutathione
Polyamine
UPR (Unfolded protein response)
Ionophore
ATP synthase
HMG-CoA reductase
Nox (NADH/NADPH oxidase)
ER/Golgi
DNA
Phospholipase
GPCR
Cytoskeleton
Topoisomerase
PPAR
Leukotriene receptor
Protease
Lipase
Kinase
Lysosome
Ion channel
Acetyltransferase
Cytochrome/MDR
Phosphatase
Retinoid receptor and related
Protein deacetylase
PDE (Phosphodiesterase)
Transcription factor
Nucleic acid methylation
PROTAC
Sugar kinase
Ribosome
PARP
Guanylyl cyclase
Chelator
DUB (Deubiquitinating enzyme)
ATPase
GTPase
Bcl-2
Monoamine oxidase
Dopamine
Glycosylation
COX (Cyclooxygenase)
Lysyl oxidase
Ubiquitin ligase
Antioxidant
Energy production
PPIase
Antibiotic
Proteasome
LOX (Lipoxygenase)
Monoamine receptor
Acetylcholinesterase/Butyrylcholinesterase
HSP (Heat shock protein)
GABAA receptor
Pathway
-- Any ---
PPAR
cAMP / cGMP signaling
Chromatin
Apoptosis inducer
Cell cycle
Leukotriene
Fatty acid metabolism
Sodium channel
Cholesterol metabolism
EGF
Lipid signaling
AKT
Proliferation
Apoptosis inhibitor
GSK3
Redox
Cell migration
Autophagy
NFkappaB
Cytokine
Transcription
PI3K
Calcium signaling
DNA synthesis
TNF
Coagulation
Cation channel
Potassium channel
Warburg effect
Intracellular transport
TGF-beta
Ion channels
Hedgehog
Estrogen
DNA damage
ACh (Acetylcholine) signaling
Degradation
mTOR
NAD, NADP pathways
Protein synthesis
Mitochondrial function
Cytotoxicity
Carbohydrate metabolism
Histamine
Necroptosis
Cannabinoid receptor
Neurotrophin
Bcl
Sphingolipid metabolism
Wnt
Cell adhesion
DNA repair
Posttranslational modification
Nucleoside/tide biosynthesis
SMAD
p53
Ferroptosis
Apoptosis
Nuclear transport
ERK
Amino acid metabolism
AMPK pathway
JNK pathway
VEGF
Notch
Chloride channel
JAK/STAT
Glycation
MAPK
Mitophagy
GlcNAc
TLR signaling
NFAT
Proton channel
Paraptosis
Senescence
Pyroptosis
Myc
Cuproptosis
Glucose metabolism
Disulfidptosis
PPAR
Beta-catenin
Cytoskeleton
IDO/TDO pathways
RANKL
Necrosis
JNK/STAT
cGMP
Eryptosis
Anoikis
Anion channel
AMPK
Apoptosis inhibitors
Oxidative stress
Senolytic agent
Lipid metabolism
Post-translational modification
PKC
Spliceosome