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Heterobifunctional Cross-Linkers

Download the Crosslinkers Handbook & Selection Guide

 

Cross-linkers with two different reactive ends
ρ-Azidobenzoyl Hydrazide Features Molecular Weight: 177.19 Spacer Arm (Å): 11.9 Reactive Toward: Carbohydrates Membrane Permeable: YES Water Soluble: NO Cleavable/ Reversible: NO                       ..
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N-5-Azido-2-nitrobenzyloxysuccinimide    Features Molecular Weight: 305.20 Spacer Arm (Å): 7.7 Reactive Toward: Primary Amines Membrane Permeable: YES Water Soluble: NO Cleavable/ Reversible: No..
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APDP A sulfhydryl-reactive and photoreactive cross-linker   Features Chemical Name: N-[4-(p-Azidosalicylamido)butyl]-3’-(2’-pyridyldithio)propionamide Synonym: APDP Formula: C₁₈H₂₀N₆O₂ Molecular Weight: 446.55 Spacer Arm: 21.0Å Reactive Toward: sulfhydryl and amino..
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EDC is a heterobifunctional, water-soluble, zero-length carbodiimide crosslinker that is used to couple carboxyl groups to primary amines. EDC activates carboxyl groups first and forms amine reactive O-acylisourea imtermediate that spontaneously reacts with primary amines to form an amide bond and i..
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N-(ε-Maleimidocaproic acid) hydrazide   Features Molecular Weight: 225.24 Spacer Arm (Å): 11.8 Reactive Toward: Sulfhydryl + Carbohydrate Membrane Permeable: Not tested  Water Soluble: NO Cleavable/ Reversible: NO    ..
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N-(ε-Maleimidocaproyloxy) succinimide ester   Features Molecular Weight: 308.29 Spacer Arm (Å): 9.4 Reactive Toward: Primary Amine + Sulfhydryl Membrane Permeable: YES Water Soluble: NO Cleavable/ Reversible: NO    ..
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N-γ-Maleimidobutyryloxysuccinimide ester     Features Molecular Weight: 280.23 Spacer Arm (Å): 6.8 Reactive Toward: Primary Amine + Sulfhydryl Membrane Permeable: YES Water Soluble: NO Cleavable/ Reversible: NO    ..
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Maleimide PEG succinimidyl carboxymethyl   Features Molecular Weight: ~3400 Reactive Toward: Primary Amine + Sulfhydryl  Membrane Permeable: Not tested  Water Soluble: NO Cleavable/ Reversible: NO    ..
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m-Maleimidobenzoyl-N-hydroxysuccinimide ester   Ideal for hapten-carrier protein, toxin-antibody, enzyme-antibody crosslinking   Features Molecular Weight: 314.25 Spacer Arm (Å): 9.9 Reactive Toward: Primary Amine + Sulfhydryl  Membrane Permeable: YES ..
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N-Hydroxysuccinimidyl-4-azidosalicyclic acid   Features Molecular Weight: 276.21 Spacer Arm (Å): 8.0 Reactive Toward: Primary Amines Membrane Permeable: YES Water Soluble: NO Cleavable/ Reversible: NO    ..
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N-(ρ-Maleimidophenyl) isocyanate   Features Molecular Weight: 214.18 Spacer Arm (Å): 8.7 Reactive Toward: Sulfhydryl + Hydroxyl Membrane Permeable: Not tested  Water Soluble: NO Cleavable/ Reversible: NO    ..
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N-Succinimidyl(4-iodoacetyl)aminobenzoate   Ideal for enzyme-antibody crosslinking   Features Molecular Weight: 402.14 Spacer Arm (Å): 10.6 Reactive Toward: Primary Amine + Sulfhydryl Membrane Permeable: YES Water Soluble: NO Cleavable/ Reversible: NO   &..
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