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Amino Acid Side Chain Modifiers

Download the Crosslinkers Handbook & Selection Guide            Download the Protein Labeling & Conjugation Handbook

 

A range of chemicals that modify amino acid side chains to block side chain interactions, change the charge or modify them to be more favorable for other reactions.

L-Cysteine hydrochloride salt is routinely used with Ellman's Reagent assays as a sulfhydryl standard. In addition, it is also used as a supplemen..
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HPG (p-hydroxyphenylglyoxal) reacts to specifically modify arginine residues under mild conditions to yield spectrophotometrically measurable signal f..
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TNBS (2,4,6-trinitrobenzene sulfonic acid) is a highly sensitive and rapid chemical used to quantitate the free amino groups.  The reaction of TN..
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1-Fluoro-2,4-dinitrobenzene [DNFB], commonly known as Sanger’s reagent is a chemical amino acid modifier that reacts with N-terminal amino acid ..
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G-Biosciences Carboxylation Kit With Citraconic Anhydride is designed for reversible blocking of primary amines so that directed conjugation or labeli..
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Citraconic anhydride reacts with primary amines and blocks them by creating an amide linkage and a terminal carboxylate.   The linkage is stabl..
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Oxidative Modification Kit is designed for the modification of glycoproteins to reactive aldehydes for amine- and hydrazide- labeling. Sodium metaperi..
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G-Biosciences Protein Acetylation Kit is designed for modifying proteins by blocking their primary amines. The NHS ester group of Sulfo NHS Acetate re..
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Reactive Amination Kit is designed to prepare amine-reactive esters of carboxylate groups for chemical labeling. Sulfo-NHS is used to generate amine r..
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SATA is used to add protected sulfhydryls to primary amines. Kit related to SATA is also available [Sulfhydration Kit With SATA] Features ..
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Sodium metaperiodate, or sodium m-periodate, is a mild oxidant that is routinely used for the conversion of cis-glycol groups in carbohydrates to reac..
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Sulfhydration Kit With SATA is designed to introduce sulfhydryls into proteins, peptides, antibodies and other molecules which are used in conjugation..
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Sulfhydration Kit With Traut's Reagent is designed for modifying primary amine group of proteins to sulfhydryl group using Traut’s Reagent. ..
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Sulfo NHS converts carboxyl groups to amine reactive sulfo NHS esters Kit related to Sulfo NHS is also available [Reactive Amination Kit]   Fe..
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Sulfo NHS Acetate blocks primary amines by acylation. Kits related to Sulfo NHS Acetate is also available [Protein Acetylation Kit]   Fea..
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Traut's Reagent adds sulfhydryls groups to primary amines    Kit related to Traut's Reagent is also available [Sulfhydra..
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