C-Reactive Protein Purification

Immobilized p-Aminophenyl Phosphoryl Choline consists of a phosphoryl choline covalently linked to beaded agarose and is designed for the purification of C-reactive protein from plasma, ascites and other biological fluids. A more economical substitute for Immoblized p-Aminophenyl Phosphoryl Choline is Immobilized O-Phosphorylethanolamine. 

Also available is a Recombinant Human C-Reactive Protein, produced in an E. coli expression system and the target gene encoding Gln19-Pro224 is expressed with a 6XHis tag at the C-terminus.

CRP, C-reactive protein, is a pentameric protein found in the blood, the levels of which rise in response to inflammation, making CRP an acute-phase protein. Its physiological role is to bind to phosphocholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system.