Apoptosis Assays & Accessories

Our Apoptosis Assays & Accessories section includes a wide variety of research products.

A wide range of apoptosis assays and accesories are available including Apoptotic DNA Ladder, caspase substrates and caspase uninduced lysates.
 
A selection of apoptosis inducers including caspase inhibitors are also available.


 
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Actinomycin D

A class of polypeptide antibiotics isolated from the Steptomyces soil bacteria.  Actinomycin D inhibits transcription by binding to DNA at the transcription initiation complex and therefore preve..

Apoptotic Inducer Set

Ready-to-use high quality apoptosis inducers allow users an easy tool for induction of apoptosis in cultured cells. These stabilized reagent solutions have a long storage life and are easy to use. The..

Camptothecin

4-ethyl-4-hydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b] quinoline-3,14-(4H,12H)-dione     A cytotoxic quinoline alkaloid that inhibits the DNA enzyme topoisomerase I (Topo I)...

CasPASE Apoptosis Colorimetric Assay™

The CasPASE™ Apoptosis Colorimetric Assay provides a simple and easy to follow method for assaying caspases 1-10, a key early indicator of apoptosis in mammalian cells.   The assay is bas..

Caspase Inhibitors

The inhibitors are potent fluoromethyl ketone (FMK) based, non-toxic, and membrane permeable. Inhibitors are supplied as 1mM ready-to-use solutions and are recommended for use at 1µl/ml cell cul..

Caspase Substrates

The caspase substrates are AFC-substrates that exhibit both fluorescence and absorbance spectral shifts between the substrate-conjugate and the free dye (AFC), and are suitable for fluorescence reader..

Caspase Uninduced Lysate

Caspase Uninduced Lysate is a simple tool for studying apoptosis and acts as an ideal negative control.   Caspase activity assays are one of the regular methods used for studying the apoptosis ..

Cycloheximide

(4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione)     An inhibitor of protein synthesis by interfering with the translocation step (movement of two..

Dexamethasone

(9-fluoro-11β,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione)     A potent and stable glucocorticoid steroid hormone that is often used as an anti-inflammatory and anti-rheum..

Doxorubicin

((8S,10S)-10-(4-amino-5-hydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione)     Doxorubicin (or hydroxyl..

Etoposide

(4’-demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside], 4’ -(dihydrogen phosphate))     An inhibitor of topoisomerase II.     Supplied as..

Recombinant Human Caspases

Recombinant human caspases 1-3 and 6-10 are supplied lyophilized in quantities of 25 units.   One unit of the specific recombinant caspase is the enzyme activity that cleaves 1nmol of a specifi..