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Non Ionic Detergents

Download the Detergents Handbook & Selection Guide for Complete Listings


Non-ionic detergents have a hydrophilic head group that is uncharged and are preferred for their ability to break lipid-lipid and lipid-protein interactions. They have limited ability to break protein-protein interactions and are often referred to as non-denaturing detergents and are used to isolate biologically active membrane proteins.


The non-ionic deteregents are supplied as a general Research Grade, Proteomic Grade (PG) Solutions and 2D-Detergents™. The Proteomic Grade (PG) Solutions have ultra low aldehyde (<100μM) and peroxide (<50μM) concentrations to reduce the effects of  peroxidase and carbonyl compounds that negatively interact with membrane proteins. The 2D-Detergents™ have low conductivity (<10μS) and ultra low aldehyde (<100μM) and peroxide (<50μM) concentrations.

Nonidet® P-40 Substitute Nonidet® P-40 Substitute is a non-ionic detergent that is provided for research purposes or as a 10% proteomic grade solution. Proteomic Grade: DG001, DG002, DG501, DG514 Research Grade: 786-511, 786-512   Proteomic Grade Detergent Soluti..
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