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Non-Ionic Detergents

Non-ionic detergents have a hydrophilic head group that is uncharged and are preferred for their ability to break lipid-lipid and lipid-protein interactions. They have limited ability to break protein-protein interactions and are often referred to as non-denaturing detergents and are used to isolate biologically active membrane proteins.

 

The non-ionic detergents are supplied as a general Research Grade, Proteomic Grade (PG) Solutions and 2D-Detergents™. The Proteomic Grade (PG) Solutions have ultra low aldehyde (<100μM) and peroxide (<50μM) concentrations to reduce the effects of  peroxidase and carbonyl compounds that negatively interact with membrane proteins. The 2D-Detergents™ have low conductivity (<10μS) and ultra low aldehyde (<100μM) and peroxide (<50μM) concentrations.

 

Download the Detergents Handbook & Selection Guide for Complete Listings

Type: Non-ionic detergent   Full Name: N,N-Bis[3-(D-gluconamido)propyl]cholamide   Molecular Formula: C42H75N3O16   Molecular Weight: 878.1   Form: Fine colorless crystals   Purity: >99%   Solubility: Water soluble   Conductivity: <25µS in..
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Brij® 35 Brij® 35 is a non-ionic detergent that is provided for research purposes or as a 10% proteomic grade solution. Proteomic Grade: DG003, DG004, DG503, DG515 Research Grade: 786-521, 786-351   Proteomic Grade Detergent Solutions Many commercial grade detergents contai..
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Brij® 58 Brij® 58 is a non-ionic detergent that is provided for research purposes or as a 10% proteomic grade solution. Proteomic Grade: DG005, DG006, DG505, DG516 Research Grade: 786-522, 786-352   Proteomic Grade Detergent Solutions Many commercial grade detergents contain..
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Type: Non-ionic detergent   Full Name: N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide   Molecular Formula: C42H75N3O15   Molecular Weight: 862.1   Form: White powder   Purity: >95%   Solubility: Water soluble   Critical micelle concentration (CMC):..
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Type: Non-ionic detergent   Full Name: N-Decanoyl-N-methylglucamine   Molecular Formula: C17H35NO6   Mol Weight: 349..46   Form: White powder   Purity: >99%   Solubility: Water soluble   Critical micelle concentration (CMC): 6-7mM (25°C) ..
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Type: Non-ionic detergent   Full Name: Octanoyl-N-methylglucamide   Molecular Formula: C15H31NO6   Molecualr Weight: 321.4   Form: White powder   Purity: >99%   Solubility: Water soluble   Critical micelle concentration (CMC): 58mM (25°C) &nbs..
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Type: Non-ionic detergent   Full Name: Nonaoyl-N-methylglucamide   Mol. Formula: C16H33NO6   Mol Weight: 335.4   Form: White powder   Purity: >99%   Solubility: Water soluble   Critical micelle concentration (CMC): 19-25mM (25°C)   Appl..
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Type: Non-ionic detergent   Full Name: N-Octyl-beta-D-glucopyranoside   Molecular Formula: C14H28O6   Molecular Weight: 292.4   Form: White to off white powder   Purity: >98%   Solubility: Water soluble   Critical micelle concentration (CMC): 20-25..
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Trition® X-114 Triton® X-114 is a non-ionic detergent that is provided for research purposes or as a 10% proteomic grade solution. Proteomic Grade: DG009, DG010, DG509, DG518 Research Grade: 786-515, 786-516   Proteomic Grade Detergent Solutions Many commercial grade deterg..
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Tween® 80 Tween® 80 is a non-ionic detergent that is provided for research purposes or as a 10% proteomic grade solution. Proteomic Grade: DG013, DG014, DG513, DG520 Research Grade: 786-519, 786-520   Proteomic Grade Detergent Solutions Many commercial grade detergents contain e..
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Nonidet® P-40 Substitute Nonidet® P-40 Substitute is a non-ionic detergent that is provided for research purposes or as a 10% proteomic grade solution. Proteomic Grade: DG001, DG002, DG501, DG514 Research Grade: 786-511, 786-512   Proteomic Grade Detergent Solutions Many co..
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Gene/Protein:
Trition® X-100 Triton® X-100 is a non-ionic detergent that is provided for research purposes or as a 10% proteomic grade solution. Proteomic Grade: DG007, DG008, DG507, DG517 Research Grade: 786-513, 786-514   Proteomic Grade Detergent Solutions Many commercia..
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